i am working on a macro that will run around and harvest at 10 locations with rest etc, however, i've noticed that its important that the macro begins to look at exactly the right pixel or after 2-3 nodes it will fail and start missing nodes.. is there a way to make sure i am always looking at exactly the same position/pixel (the place to stand is fixed, that is not a problem)
and if actool or whatever cant handle this, is there an external program that can ?

You might have better luck posting your question on a Deicated Forum supporting Darkfall Macro's.

http://darkfallmacros.com/

And if ACTool can't do what your looking for, your next best bet is that AutoIt can, and they also have a sub-forum on the above link.